Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | CENPE | Q02224 | 3/20 | 0.34 |
| ▸ | TACR1 | P25103 | 4/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27371705 | 0.83 | CENPE (0.48) | CENPETACR1GRIA2GRIA4MAPK14 | |
| SCHEMBL27371087 | 0.79 | MAPK14 (0.35) | TP53LIPGMAPK14HTTNCOA3 | |
| SCHEMBL27375508 | 0.79 | CENPE (0.35) | TP53CENPETACR1GRIA2GRIA4 | |
| SCHEMBL7843260 | 0.77 | GABRA2 (0.41) | CENPETACR1MEN1ALDH1A1MAPT | |
| SCHEMBL7851323 | 0.76 | GRIA4 (0.44) | CENPETACR1GRIA2GRIA4MAPK14 | |
| SCHEMBL27539886 | 0.67 | ADORA3 (0.41) | TP53TACR1HTTALDH1A1MAPT | |
| SCHEMBL31590072 | 0.64 | BRD4 (0.46) | — | |
| SCHEMBL30008443 | 0.63 | CHRNA7 (0.38) | MAPK14SMN1; SMN2 | |
| SCHEMBL30218351 | 0.62 | POLB (0.37) | GRIA2GRIA4MAPK14MEN1KMT2A | |
| SCHEMBL14809648 | 0.62 | MEN1 (0.42) | TP53CENPETACR1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052004-C | Heterocyclic compounds, their production and use | TALCEDA CHEMICAL IND LTD (JP) | 2000-05-03 | — | — | CN | disclosed |
| CN-1107476-A | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-08-30 | — | — | CN | disclosed |