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Tryptophan

Tryptophan

SCHEMBL27376884

CC(C)C[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)O.C[C@@H](O)[C@H](N)C(=O)O.N=C(N)NCCCC(N)C(=O)[O-].N=C(N)NCCCC(N)C(=O)[O-].NCCCC[C@H](N)C(=O)O.N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O.[Ca+2]

nearest known ligand 0.42

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Known targets — ChEMBL curated mechanism

ACES1PR1S1PR4S1PR5

The experimentally established mechanism targets of Tryptophan. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ PTH1R Q03431 8/20 0.42
▸ KEAP1 Q14145 1/20 0.42
▸ IL23R Q5VWK5 5/20 0.41
▸ RXFP1 Q9HBX9 1/20 0.41
▸ GLP1R P43220 2/20 0.40
▸ GCGR P47871 1/20 0.40
▸ GIPR P48546 1/20 0.40
▸ GHSR Q92847 2/20 0.40
▸ NPY2R P49146 1/20 0.40
▸ CCKBR P32239 1/20 0.39
▸ CTSC P53634 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptophan SCHEMBL28979632 0.90 KDM4E (0.45) GHSR
Tryptophan SCHEMBL27432308 0.90 KEAP1 (0.43) PTH1RKEAP1IL23RRXFP1GLP1R
Tryptophan SCHEMBL27493966 0.88 KEAP1 (0.42) PTH1RKEAP1IL23RRXFP1GLP1R
Dl-Tryptophan SCHEMBL27369426 0.88 MEN1 (0.43) GHSRCTSC
Tryptophan SCHEMBL9010812 0.88 MEN1 (0.43) GHSRCTSC
Tryptophan SCHEMBL27546659 0.87 KEAP1 (0.41) PTH1RKEAP1IL23RGLP1R
Dl-Tryptophan SCHEMBL27344693 0.87 MEN1 (0.48) GHSRCTSC
Tryptophan SCHEMBL27389650 0.87 TUBB4A (0.44) PTH1RIL23RGLP1RGCGRGIPR
Tryptophan SCHEMBL27434560 0.86 GLP1R (0.49) PTH1RKEAP1IL23RRXFP1GLP1R
Dl-Tryptophan SCHEMBL27444819 0.85 MEN1 (0.46) GHSRCTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1062268-A A kind of production method of full-nutrient fast-food powder COOPERATION DEPARTMENT OF SCIE (CN) 1992-07-01 — — CN disclosed
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