Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 3/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 9/20 | 0.37 |
| ▸ | METTL14 | Q9HCE5 | 9/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27384011 | 0.87 | EIF4A3 (0.46) | EIF4A3METTL3METTL14SMN1; SMN2RAB9A | |
| SCHEMBL27247390 | 0.84 | METTL3 (0.39) | METTL3METTL14SMN1; SMN2RAB9AMTNR1A | |
| SCHEMBL27246874 | 0.83 | HRH4 (0.40) | METTL3METTL14SMN1; SMN2RAB9AMTNR1A | |
| SCHEMBL27247738 | 0.83 | METTL3 (0.38) | METTL3METTL14SMN1; SMN2RAB9AMTNR1A | |
| SCHEMBL30920223 | 0.83 | HRH4 (0.40) | METTL3METTL14SMN1; SMN2RAB9AMTNR1A | |
| SCHEMBL27383634 | 0.83 | DAO (0.46) | METTL3METTL14SMN1; SMN2RAB9A | |
| SCHEMBL30920709 | 0.81 | MTNR1A (0.57) | SMN1; SMN2RAB9AMTNR1AMTNR1BNPC1 | |
| SCHEMBL27382616 | 0.80 | EIF4A3 (0.51) | EIF4A3METTL3METTL14SMN1; SMN2RAB9A | |
| SCHEMBL27383362 | 0.80 | RAB9A (0.38) | EIF4A3METTL3METTL14SMN1; SMN2RAB9A | |
| SCHEMBL27247777 | 0.80 | SMN1; SMN2 (0.36) | EIF4A3METTL3METTL14SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |