Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27395625 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TDP1HTTL3MBTL1GFER | |
| SCHEMBL14028821 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TDP1HTTL3MBTL1GFER | |
| SCHEMBL27418397 | 0.83 | HTT (0.50) | ALDH1A1TDP1HTTL3MBTL1GFER | |
| SCHEMBL27395622 | 0.82 | TSHR (0.56) | ALDH1A1TDP1HTTL3MBTL1MAPK1 | |
| SCHEMBL14159539 | 0.82 | ALDH1A1 (0.80) | ALDH1A1TDP1HTTL3MBTL1GFER | |
| SCHEMBL10013917 | 0.82 | ALDH1A1 (0.80) | ALDH1A1TDP1HTTL3MBTL1GFER | |
| SCHEMBL2173776 | 0.80 | CA2 (0.62) | MMP14LTA4HFFAR1 | |
| Phosphoric Acid SCHEMBL9308118 | 0.79 | HTT (0.56) | ALDH1A1TDP1HTTL3MBTL1GFER | |
| SCHEMBL822034 | 0.78 | ALDH1A1 (0.74) | ALDH1A1TDP1HTTL3MBTL1GFER | |
| SCHEMBL30195024 | 0.78 | ALDH1A1 (0.74) | ALDH1A1TDP1HTTL3MBTL1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1089614-A | Alpha-phosphonosulfonate squalene synthetase inhibitors and method | SQUIBB & SONS INC (US) | 1994-07-20 | — | — | CN | disclosed |