SCHEMBL2173776

SCHEMBL2173776

O=P(O)(O)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.62
CA4 P22748 1/20 0.62
CA5A P35218 1/20 0.62
MMP2 P08253 3/20 0.53
CA9 Q16790 3/20 0.53
MMP8 P22894 1/20 0.53
MMP14 P50281 1/20 0.53
CA14 Q9ULX7 1/20 0.53
LTA4H P09960 4/20 0.52
TSHR P16473 1/20 0.52
NR1H2 P55055 1/20 0.52
BAX Q07812 1/20 0.52
SRC P12931 1/20 0.50
PARP10 Q53GL7 1/20 0.48
PGR P06401 1/20 0.47
SRD5A2 P31213 1/20 0.47
CA1 P00915 3/20 0.47
MAOA P21397 1/20 0.46
CA12 O43570 2/20 0.46
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11050917 0.87 MMP2 (0.53) CA2CA4CA5AMMP2CA9
Diphenylether SCHEMBL356479 0.84 LTA4H (0.67) CA2CA4CA5AMMP2CA9
Diphenylether SCHEMBL17801642 0.84 LTA4H (0.67) CA2CA4CA5AMMP2CA9
SCHEMBL27604199 0.83 CA9 (0.50) CA2MMP2CA9MMP8MMP14
SCHEMBL3833973 0.82 LTA4H (0.57) CA2MMP2CA9MMP8MMP14
SCHEMBL10849592 0.82 CA2 (0.56) CA2CA4CA5AMMP2CA9
Diphenylether SCHEMBL27662442 0.81 LTA4H (0.63) CA2CA4CA5AMMP2CA9
Diphenylether SCHEMBL27797017 0.81 LTA4H (0.63) CA2CA4CA5AMMP2CA9
Diphenylether SCHEMBL28278866 0.81 LTA4H (0.63) CA2CA4CA5AMMP2CA9
SCHEMBL15789527 0.81 GPR84 (0.46) CA2CA4CA5AMMP2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103415586-B Polyester resin composition for electrical/electronic component sealing material, package, and method for producing same TOYOBO CO.,LTD. (JP) 2016-04-06 CN disclosed
CN-103415586-A Polyester resin composition for electrical/electronic component sealing material, package, and method for producing same TOYO BOSEKI 2013-11-27 CN disclosed
US-7973109-B2 Crosslinked type layered metal phosphonate compound, production process therefor, non-crosslinked type layered metal phosphonate compound, production process therefor, as well as stock solution KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2011-07-05 US disclosed
US-20090093607-A1 Crosslinked type layered metal phosphonate compound, production process therefor, non-crosslinked type layered metal phosphonate compound, production process therefor, as well as stock solution KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2009-04-09 US disclosed
CN-1507450-A Novel cyclo azaphospha hydrocarbons ������ҩ�����޹�˾ 2004-06-23 CN disclosed
EP-0487343-B1 Process for preparing a lithographic plate FUJI PHOTO FILM CO LTD (JP) 1999-04-28 EP disclosed
EP-0487343-A1 Process for preparing a lithographic plate Fuji Photo Film Co., Ltd. (JP) 1992-05-27 EP disclosed
US-4655883-A ANODIZING AN AROMATIC COMPOUND IN THE PRESENCE OF A PHOSPHITE AND ALKANOL IN A ELECTROLYTIC CELL HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-07 US disclosed
US-4434108-A POSTEMERGENCE AND PREEMERGENCE HERBICIDES CIBA-GEIGY CORPORATION (US) 1984-02-28 US disclosed
US-4421548-A Herbicidally active 2-substituted 5-penoxyphenylphosphonic acid derivatives CIBA-GEIGY CORPORATION (US) 1983-12-20 US disclosed
US-4420436-A HERBICIDES; PLANT GROWTH REGULATORS CIBA-GEIGY CORPORATION (US) 1983-12-13 US disclosed
US-4391624-A 2-NITRO-2',6'-DICHLORO-4'-TRIFLUOROMETHYL SUBSTITUTED CIBA-GEIGY CORPORATION (US) 1983-07-05 US disclosed
US-4322375-A HERBICIDES; PLANT GROWTH REGULATORS; DESICCANTS CIBA-GEIGY CORPORATION (US) 1982-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090093607-A1 Crosslinked type layered metal phosphonate compound, production process therefor, non-crosslinked type layered metal phosphonate compound, production process therefor, as well as stock solution WEE1, WEE2, PPIP5K2 CA2 2108/4885CA4 2196/4885CA5A 1396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.