Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461433 | 0.85 | LMNA (0.43) | TSHRALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL5450319 | 0.81 | TSHR (0.61) | TSHRALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL793986 | 0.78 | TSHR (0.56) | TSHRALDH1A1NPC1TDP1MAPT | |
| SCHEMBL712779 | 0.78 | ALDH1A1 (0.59) | TSHRALDH1A1NPC1RAB9ASLC6A2 | |
| SCHEMBL10514885 | 0.76 | TSHR (0.54) | TSHRALDH1A1NPC1MAPTMAOB | |
| SCHEMBL21596609 | 0.76 | TSHR (0.54) | TSHRALDH1A1NPC1RAB9ASLC6A2 | |
| SCHEMBL8621465 | 0.76 | ALDH1A1 (0.57) | TSHRALDH1A1NPC1SLC6A2SLC6A3 | |
| SCHEMBL10514891 | 0.76 | TSHR (0.54) | TSHRALDH1A1NPC1MAPTMAOB | |
| SCHEMBL657234 | 0.76 | TDP1 (0.55) | TSHRALDH1A1NPC1RAB9ASLC6A2 | |
| Hydrogen Peroxide SCHEMBL28758135 | 0.75 | TSHR (0.94) | TSHRALDH1A1SLC6A2SLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1494906-A | Application of compound in preparation of medicine for preventing and curing multiple drug resistance | ��̩��˹ҩ��ɷ�����˾ | 2004-05-12 | — | — | CN | disclosed |
| CN-1086386-C | Multi-drug resistance modifiers | VERTEX PHARMA (US) | 2002-06-19 | — | — | CN | disclosed |
| CN-1088577-A | Novel multi-drug resistance modifiers | VERTEX PHARMA (US) | 1994-06-29 | — | — | CN | disclosed |