Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27930519 | 0.85 | FABP3 (0.41) | SMN1; SMN2LMNACYP1A2CYP3A4NPC1 | |
| SCHEMBL28802185 | 0.79 | CYP3A4 (0.44) | SMN1; SMN2ALDH1A1LMNAHPGDCYP3A4 | |
| SCHEMBL30159162 | 0.79 | FABP3 (0.41) | ALDH1A1LMNACYP1A2TSHRMAPK1 | |
| SCHEMBL28110787 | 0.79 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL29640023 | 0.79 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL28448795 | 0.79 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1KDM4ELMNAGLA | |
| SCHEMBL27685032 | 0.78 | NPC1 (0.52) | SMN1; SMN2ALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL27396073 | 0.77 | CYP1A1 (0.51) | SMN1; SMN2ALDH1A1KDM4ELMNAGLA | |
| SCHEMBL20108554 | 0.77 | FABP4 (0.53) | ALDH1A1LMNATSHRPTGS1PTGS2 | |
| SCHEMBL28155065 | 0.76 | MAPT (0.42) | SMN1; SMN2ALDH1A1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1091420-A | Process for the preparation of diphenylamine derivatives | YONGXIN MEDICINES AND CHEMICAL (CN) | 1994-08-31 | — | — | CN | disclosed |