Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.39 |
| ▸ | FLT3 | P36888 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27399107 | 0.86 | PTGS2 (0.36) | TGFBR1PTGS2FLT3PIK3CA | |
| SCHEMBL27399097 | 0.78 | TGFBR1 (0.47) | TGFBR1PTGS2GRM2PIK3CA | |
| SCHEMBL14041215 | 0.76 | TGFBR1 (0.43) | TGFBR1ADORA2AADORA1ADORA2BFLT3 | |
| SCHEMBL31051205 | 0.75 | TGFBR1 (0.41) | TGFBR1PTGS2FLT3PIK3CA | |
| SCHEMBL31051278 | 0.73 | FLT3 (0.36) | TGFBR1PTGS2ADORA2AADORA1ADORA2B | |
| SCHEMBL27399217 | 0.73 | ADORA2A (0.47) | TGFBR1ADORA2AADORA1ADORA2B | |
| SCHEMBL27399088 | 0.72 | PTGS2 (0.54) | TGFBR1PTGS2ADORA2AADORA1ADORA2B | |
| SCHEMBL27398657 | 0.71 | FLT3 (0.39) | TGFBR1ADORA2AADORA1ADORA2BFLT3 | |
| SCHEMBL24155891 | 0.68 | ADORA2A (0.44) | TGFBR1ADORA2AADORA1ADORA2BFLT3 | |
| SCHEMBL27399170 | 0.68 | TGFBR1 (0.43) | TGFBR1ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126404-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-20 | — | — | WO | disclosed |