Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5467244 | 0.89 | SLC18A3 (0.48) | SLC18A3SIGMAR1POLBMAPTGAA | |
| Hydrochloric Acid SCHEMBL2803164 | 0.87 | SLC18A3 (0.47) | SLC18A3SIGMAR1POLBMAPTGAA | |
| SCHEMBL3648603 | 0.82 | HTR3A (0.44) | SLC18A3SIGMAR1POLBMAPTGAA | |
| SCHEMBL1554818 | 0.76 | POLB (0.50) | HCAR2POLBMAPTGAAALDH1A1 | |
| Tert-Butyl Formate SCHEMBL27766934 | 0.75 | ALDH1A1 (0.39) | SLC18A3SIGMAR1POLBMAPTGAA | |
| SCHEMBL497608 | 0.74 | — | — | |
| SCHEMBL17474594 | 0.74 | MAPT (0.39) | HCAR2MAPTBRD4 | |
| Acetic Acid SCHEMBL11173187 | 0.74 | BRD4 (0.47) | HCAR2POLBMAPTGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11286601 | 0.72 | — | — | |
| SCHEMBL7014154 | 0.71 | HTR6 (0.45) | POLBMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1052674-A | New heterogeneous ring compound | NOVO NORDISK AS (DK) | 1991-07-03 | — | — | CN | disclosed |