Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | TGM1 | P22735 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 2/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30835888 | 0.88 | TEAD1 (0.42) | HRH3TEAD1HPGDSMN1; SMN2 | |
| SCHEMBL27401246 | 0.88 | TEAD1 (0.42) | HRH3TEAD1HPGDSMN1; SMN2 | |
| SCHEMBL30835927 | 0.77 | RORC (0.43) | HRH3SCN9ALIPEHCRTR1HCRTR2 | |
| SCHEMBL27401285 | 0.77 | RORC (0.43) | HRH3SCN9ALIPEHCRTR1HCRTR2 | |
| Trifluoroacetic Acid SCHEMBL30835928 | 0.69 | KMT2A (0.38) | KDM4EABL1LMNAKMT2ASCN9A | |
| SCHEMBL265343 | 0.69 | KMT2A (0.43) | KDM4EKMT2ATGM2HPGDSMN1; SMN2 | |
| SCHEMBL27399148 | 0.68 | TEAD1 (0.47) | HRH3TEAD1 | |
| SCHEMBL15435161 | 0.67 | KMT2A (0.46) | KDM4EABL1LMNAKMT2AHPGD | |
| SCHEMBL955290 | 0.67 | KMT2A (0.42) | KDM4EKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL955289 | 0.67 | KMT2A (0.42) | KDM4EKMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |