Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 2/20 | 0.34 |
| ▸ | CDK8 | P49336 | 2/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27399008 | 0.86 | PIK3CA (0.39) | SMN1; SMN2TOP1TRPV1ADORA2AADORA1 | |
| SCHEMBL27399917 | 0.84 | DHODH (0.34) | DHODHLCKBTKSMN1; SMN2L3MBTL1 | |
| SCHEMBL27399014 | 0.83 | LCK (0.51) | DHODHCYP11B2LCKBTKABL1 | |
| SCHEMBL27399603 | 0.80 | MKNK1 (0.40) | DHODHLCKBTKSMN1; SMN2L3MBTL1 | |
| SCHEMBL27399330 | 0.78 | DHODH (0.39) | DHODHCYP11B2LCKBTKABL1 | |
| SCHEMBL27400004 | 0.78 | IKBKB (0.35) | LCKBTKLIMK1IKBKB | |
| SCHEMBL27398651 | 0.77 | LCK (0.37) | DHODHLCKBTKABL1KDM4E | |
| SCHEMBL27399247 | 0.76 | MKNK1 (0.50) | DHODHLCKBTKSMN1; SMN2L3MBTL1 | |
| SCHEMBL27399600 | 0.75 | IRAK4 (0.35) | DHODHLCKBTKLIMK1IKBKB | |
| SCHEMBL27399933 | 0.75 | PRMT5 (0.41) | DHODHLCKBTKSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |