Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107643 | 0.77 | ALOX5 (0.39) | ALOX5TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22070111 | 0.72 | ALOX5 (0.36) | ALOX5CES2CES1KEAP1 | |
| SCHEMBL7153932 | 0.71 | GLA (0.38) | ALOX5TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9215274 | 0.70 | ALOX5 (0.44) | ALOX5CES2CES1KEAP1 | |
| SCHEMBL9879846 | 0.69 | TAAR1 (0.44) | ALOX5TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL355658 | 0.69 | — | — | |
| SCHEMBL341042 | 0.68 | GABBR2 (0.56) | ALOX5TSHRCYP3A4CYP2D6CES2 | |
| SCHEMBL2880798 | 0.68 | ALOX5 (0.39) | ALOX5SLC6A2SLC6A4SLC6A3TSHR | |
| Hydrochloric Acid SCHEMBL2712850 | 0.67 | TAAR1 (0.43) | ALOX5TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9883154 | 0.67 | SLC6A2 (0.42) | ALOX5TAAR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1086704-C | Compound having antihypertensive, cardioprotective, anti-ischemic and antilipolytic functions | AVENTIS PHARMA INC (US) | 2002-06-26 | — | — | CN | disclosed |
| CN-1148811-A | Compound having antihypertensive, cardioprotective, anti-ischemic and antilipolytic functions | RHONE POULENC RORER PHARMA (US) | 1997-04-30 | — | — | CN | disclosed |