Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27407904 | 0.82 | NNMT (0.45) | — | |
| SCHEMBL3974375 | 0.81 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2KEAP1NFE2L2HAVCR2 | |
| SCHEMBL4675608 | 0.81 | GABRP (0.41) | LMNASMN1; SMN2KEAP1NFE2L2HAVCR2 | |
| SCHEMBL1427391 | 0.81 | LMNA (0.39) | LMNASMN1; SMN2KEAP1NFE2L2HAVCR2 | |
| SCHEMBL27407989 | 0.78 | CASP1 (0.37) | LMNAKMT2A | |
| SCHEMBL25351383 | 0.77 | KEAP1 (0.42) | LMNASMN1; SMN2KEAP1NFE2L2HAVCR2 | |
| SCHEMBL3980791 | 0.76 | GABRP (0.43) | LMNASMN1; SMN2KEAP1NFE2L2HAVCR2 | |
| SCHEMBL391794 | 0.76 | KEAP1 (0.44) | LMNASMN1; SMN2KEAP1NFE2L2HAVCR2 | |
| SCHEMBL29781361 | 0.76 | GABRP (0.43) | LMNASMN1; SMN2KEAP1NFE2L2HAVCR2 | |
| SCHEMBL29418647 | 0.76 | KEAP1 (0.44) | LMNASMN1; SMN2KEAP1NFE2L2HAVCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024127363-A1 | TYK2 PSEUDOKINASE LIGANDS AND USES THEREOF | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2024-06-20 | — | — | WO | disclosed |