Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 7/20 | 0.39 |
| ▸ | NOS1 | P29475 | 5/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15757443 | 0.65 | UHRF1 (0.42) | TYMSNOS1NOS3NOS2CYP1A2 | |
| SCHEMBL20711061 | 0.59 | TYMS (0.40) | TYMSNOS1NOS3NOS2 | |
| SCHEMBL12242246 | 0.58 | — | — | |
| SCHEMBL3454196 | 0.58 | NOS1 (0.41) | NOS1NOS3NOS2 | |
| SCHEMBL10568181 | 0.58 | HPGD (0.53) | TYMS | |
| SCHEMBL12959072 | 0.57 | XDH (0.45) | TYMSCYP1A2 | |
| SCHEMBL3800890 | 0.57 | NOS1 (0.38) | TYMSNOS1NOS3NOS2 | |
| SCHEMBL19493168 | 0.57 | NPSR1 (0.45) | TYMSCYP1A2CDK5CDK5R1 | |
| SCHEMBL9166765 | 0.57 | TYMS (0.61) | TYMS | |
| SCHEMBL12710033 | 0.56 | PARP1 (0.50) | TYMSCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024119117-A1 | MODIFIED 5' CAP FOR MRNA AND METHODS OF USE THEREOF | PRIME MEDICINE, INC. (US) | 2024-06-06 | — | — | WO | disclosed |