Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 7/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2740965 | 0.89 | CRHBP (0.53) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL2740966 | 0.86 | CRHBP (0.57) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL2740946 | 0.86 | CRHBP (0.59) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL2740994 | 0.82 | L3MBTL1 (0.59) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL6351422 | 0.78 | HTT (0.67) | KMT2AMEN1GAAHTTLMNA | |
| SCHEMBL13128926 | 0.77 | IDO1 (0.57) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL2741012 | 0.76 | CRHBP (0.53) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL2740998 | 0.75 | CRHBP (0.60) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL2740971 | 0.75 | CRHBP (0.49) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL15647549 | 0.74 | NFKBIA (0.61) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088772-B2 | Sulfonamides and their use as a medicament | THE GENETICS COMPANY, INC. (CH) | 2012-01-03 | — | — | US | disclosed |