Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13128924 | 0.84 | ALDH1A1 (0.64) | ALDH1A1HTTTSHRLMNAMEN1 | |
| SCHEMBL2740967 | 0.77 | KMT2A (0.52) | IDO1POLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL13128923 | 0.74 | ALDH1A1 (0.51) | IDO1POLBALDH1A1TSHRLMNA | |
| SCHEMBL28435446 | 0.72 | ALDH1A1 (0.65) | IDO1APOBEC3GPOLBALDH1A1HTT | |
| SCHEMBL13128980 | 0.71 | L3MBTL1 (0.50) | POLBALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL21987820 | 0.70 | LMNA (0.74) | IDO1ALDH1A1HTTTSHRSMN1; SMN2 | |
| SCHEMBL29440567 | 0.70 | LMNA (0.74) | IDO1ALDH1A1HTTTSHRSMN1; SMN2 | |
| SCHEMBL4623054 | 0.69 | ALDH1A1 (0.75) | POLBALDH1A1HTTTSHRSMN1; SMN2 | |
| SCHEMBL27884389 | 0.69 | CYP2C9 (0.63) | ALDH1A1HTTTSHRLMNAMEN1 | |
| SCHEMBL9365750 | 0.69 | PKM (0.73) | IDO1ALDH1A1SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249135-A1 | SULFONAMIDES AND THEIR USE AS A MEDICAMENT | THE GENETICS COMPANY, INC. (CH) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249135-A1 | SULFONAMIDES AND THEIR USE AS A MEDICAMENT | BCOR, CBR3, SULT1E1 | IDO1 2462/4885APOBEC3G 4713/4885POLB 3742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.