Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | HTR5A | P47898 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828451 | 0.80 | DRD2 (0.45) | HTR1AHTR2ANCF1TSHRHSD17B10 | |
| SCHEMBL8828572 | 0.80 | ADRB1 (0.49) | HTR7TSHRHSD17B10ALDH1A1LMNA | |
| SCHEMBL8828393 | 0.79 | HSD17B10 (0.55) | TSHRNFKB1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL9643856 | 0.79 | HTR1A (0.74) | HTR1AHTR2AHTR7HTR3AHTR3E | |
| SCHEMBL4249373 | 0.78 | TSHR (0.56) | TSHRHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL8828348 | 0.78 | BRD9 (0.40) | HTR1AHTR2ANCF1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7203515 | 0.77 | KDM4E (0.75) | HTR1AHTR2AHTR7HTR3AHTR3E | |
| SCHEMBL8828453 | 0.77 | DRD4 (0.46) | HTR1AHTR2AHTR7CYP1A2CYP2D6 | |
| SCHEMBL8828510 | 0.77 | DRD2 (0.62) | HTR1AHTR3AHTR3EHTR3BCYP1A2 | |
| SCHEMBL8828437 | 0.77 | HTR1A (0.41) | HTR1AHTR7TSHRDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1074766-C | Alkylaminobenzothiazole and -benzoxazole derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2001-11-14 | — | — | CN | disclosed |
| CN-1218461-A | Alkylaminobenzothiazole and -benzoxazole derivatives | JANSSEN PHARMACEUTICA NV (NL) | 1999-06-02 | — | — | CN | disclosed |