Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27411159 | 0.81 | GLS (0.32) | — | |
| SCHEMBL27409296 | 0.73 | — | — | |
| SCHEMBL23193195 | 0.73 | OPRM1 (0.34) | FOLH1MMP2MMP9MMP8MMP13 | |
| SCHEMBL27409838 | 0.72 | FOLH1 (0.31) | FOLH1MMP2MMP9MMP8MMP13 | |
| SCHEMBL22561301 | 0.72 | — | — | |
| SCHEMBL27409884 | 0.69 | GLS (0.33) | — | |
| SCHEMBL25045543 | 0.69 | PARP14 (0.31) | — | |
| SCHEMBL27409581 | 0.68 | GLS (0.33) | — | |
| SCHEMBL25701620 | 0.68 | CA2 (0.34) | HPGD | |
| SCHEMBL22551273 | 0.68 | CYP1A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024123914-A1 | PROCESS FOR MAKING ANTIBODY-DRUG CONJUGATES | MERCK SHARP & DOHME LLC (US) | 2024-06-13 | — | — | WO | disclosed |