Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | F10 | P00742 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30932945 | 0.87 | HSD11B1 (0.47) | MAPTF2F10MEN1KMT2A | |
| SCHEMBL27412265 | 0.84 | F2 (0.46) | MAPTF2F10MEN1KMT2A | |
| SCHEMBL27412307 | 0.84 | HSD11B1 (0.44) | MAPTF2F10MEN1KMT2A | |
| SCHEMBL30932940 | 0.83 | HSD11B1 (0.43) | MAPTF2F10MEN1KMT2A | |
| SCHEMBL30932939 | 0.83 | HSD11B1 (0.43) | MAPTF2F10MEN1KMT2A | |
| SCHEMBL9986293 | 0.81 | F2 (0.50) | MAPTF2F10LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9987587 | 0.81 | F2 (0.49) | MAPTF2F10LMNASMN1; SMN2 | |
| SCHEMBL17925445 | 0.78 | LMNA (0.53) | MAPTF2F10MEN1KMT2A | |
| SCHEMBL30932919 | 0.76 | HSD11B1 (0.52) | F2F10LMNASMN1; SMN2TSHR | |
| SCHEMBL1271070 | 0.76 | F2 (0.67) | MAPTF2F10LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112918-A1 | RNA DEGRADERS AND USES THEREOF | ARRAKIS THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |