Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | F10 | P00742 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27412307 | 0.87 | HSD11B1 (0.44) | F2F10MAPTHSD11B1HSD17B1 | |
| SCHEMBL27412237 | 0.84 | MAPT (0.52) | F2F10MAPTHSD11B1HSD17B1 | |
| SCHEMBL30932945 | 0.83 | HSD11B1 (0.47) | F2F10MAPTHSD11B1HSD17B1 | |
| SCHEMBL30932939 | 0.79 | HSD11B1 (0.43) | F2F10MAPTHSD11B1HSD17B1 | |
| SCHEMBL30932940 | 0.79 | HSD11B1 (0.43) | F2F10MAPTHSD11B1HSD17B1 | |
| SCHEMBL9986293 | 0.74 | F2 (0.50) | F2F10MAPTHSD11B1HSD17B1 | |
| SCHEMBL27411959 | 0.74 | SIRT2 (0.39) | MAPTLMNATP53NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9987587 | 0.73 | F2 (0.49) | F2F10MAPTHSD11B1HSD17B1 | |
| SCHEMBL17925445 | 0.71 | LMNA (0.53) | F2F10MAPTHSD11B1HSD17B1 | |
| SCHEMBL30932919 | 0.69 | HSD11B1 (0.52) | F2F10HSD11B1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112918-A1 | RNA DEGRADERS AND USES THEREOF | ARRAKIS THERAPEUTICS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |