SCHEMBL30932945

SCHEMBL30932945

C#CCOc1ccc(NC(=O)Nc2nc(CC(=O)N3CCN(C)CC3)cs2)cc1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 2/20 0.47
▸ HSD17B1 P14061 1/20 0.47
▸ HSD17B2 P37059 1/20 0.47
▸ F2 P00734 4/20 0.46
▸ F10 P00742 4/20 0.46
▸ MAPT P10636 5/20 0.46
▸ LMNA P02545 2/20 0.44
▸ TP53 P04637 1/20 0.44
▸ NPC1 O15118 2/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ CTPS1 P17812 1/20 0.40
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ EPHX2 P34913 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30932940 0.92 HSD11B1 (0.43) HSD11B1HSD17B1HSD17B2F2F10
SCHEMBL30932939 0.92 HSD11B1 (0.43) HSD11B1HSD17B1HSD17B2F2F10
SCHEMBL27412237 0.87 MAPT (0.52) HSD11B1HSD17B1HSD17B2F2F10
SCHEMBL27412265 0.83 F2 (0.46) HSD11B1HSD17B1HSD17B2F2F10
SCHEMBL27412307 0.83 HSD11B1 (0.44) HSD11B1HSD17B1HSD17B2F2F10
SCHEMBL9986293 0.79 F2 (0.50) HSD11B1HSD17B1HSD17B2F2F10
Hydrochloric Acid SCHEMBL9987587 0.78 F2 (0.49) HSD11B1HSD17B1HSD17B2F2F10
SCHEMBL17925445 0.73 LMNA (0.53) HSD11B1HSD17B1HSD17B2F2F10
SCHEMBL30932919 0.72 HSD11B1 (0.52) HSD11B1HSD17B1HSD17B2F2F10
SCHEMBL1271070 0.72 F2 (0.67) HSD11B1HSD17B1HSD17B2F2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4622647-A1 RNA DEGRADERS AND USES THEREOF Arrakis Therapeutics, Inc. (US) 2025-10-01 — — EP disclosed
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