Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25808495 | 0.93 | ALOX5AP (0.39) | AKR1C3AKR1C2APPGPR3KIF11 | |
| SCHEMBL20380692 | 0.93 | AKR1C3 (0.34) | AKR1C3AKR1C2APPGPR3GRM2 | |
| SCHEMBL16866174 | 0.92 | AKR1C3 (0.37) | AKR1C3AKR1C2APPKIF11ALOX5AP | |
| SCHEMBL18735548 | 0.91 | AKR1C3 (0.33) | AKR1C3AKR1C2APPGPR3ALOX5AP | |
| SCHEMBL20380670 | 0.90 | PTGS2 (0.34) | AKR1C3AKR1C2APPGPR3KDM1A | |
| SCHEMBL18355958 | 0.89 | APP (0.38) | AKR1C3AKR1C2APPGPR3KIF11 | |
| SCHEMBL17371157 | 0.87 | ALOX5AP (0.38) | AKR1C3AKR1C2APPGPR3KIF11 | |
| SCHEMBL4432399 | 0.87 | PTPN5 (0.34) | CYP2C19 | |
| SCHEMBL20380602 | 0.85 | AKR1C3 (0.32) | AKR1C3AKR1C2APPGPR3KDM1A | |
| SCHEMBL18887655 | 0.85 | PDE3B (0.33) | AKR1C3AKR1C2APPGPR3ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043781-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-20230383186-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-11-30 | — | — | US | disclosed |
| US-20230383186-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-11-30 | — | — | US | disclosed |
| US-11739267-B2 | LC medium | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| US-11739267-B2 | LC medium | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| US-11739266-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-29 | — | — | US | disclosed |
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-08 | — | — | US | disclosed |
| US-11685863-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-06-27 | — | — | US | disclosed |
| US-20230007940-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCKP PATENT GMBH (DE) | 2023-01-12 | — | — | US | disclosed |
| US-11015121-B2 | Liquid crystal displays and liquid crystalline media with homeotropic alignment | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2021-05-25 | — | — | US | disclosed |
| US-20100224827-A1 | LIQUID-CRYSTALLINE MEDIUM | WITTEK MICHAEL | 2010-09-09 | — | — | US | disclosed |
| US-7763329-B2 | Liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-07-27 | — | — | US | disclosed |
| US-20100181533-A1 | Liquid-crystal compounds and LC media | MERCK KGAA (DE) | 2010-07-22 | — | — | US | disclosed |
| US-7658978-B2 | Liquid crystalline medium | MERCK PATENT GESELLSCHAFT (DE) | 2010-02-09 | — | — | US | disclosed |
| US-20100026953-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2010-02-04 | — | — | US | disclosed |
| US-20090289223-A1 | LIQUID-CRYSTALLINE MEDIUM | WITTEK MICHAEL | 2009-11-26 | — | — | US | disclosed |
| US-7595101-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2009-09-29 | — | — | US | disclosed |
| US-20090230354-A1 | Liquid Crystalline Medium | MERCK PATENT GESELLSCHAFT (DE) | 2009-09-17 | — | — | US | disclosed |
| WO-2009033564-A2 | ELECTRO-OPTICAL LIGHT CONTROL ELEMENT, ELECTRO-OPTICAL DISPLAY AND CONTROL MEDIUM | MERCK PATENT GMBH (DE) | 2009-03-19 | — | — | WO | disclosed |
| US-20080083904-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | VCL, ILK, LCP1 | AKR1C3 4067/4885AKR1C2 4097/4885APP 1164/4885 |
| US-11685863-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | LPXN, VCL, LCP1 | AKR1C3 3514/4885AKR1C2 3386/4885APP 482/4885 |
| US-20080083904-A1 | LIQUID-CRYSTALLINE MEDIUM | NEFM, OSBP, ALPG | AKR1C3 4649/4885AKR1C2 4664/4885APP 864/4885 |
| US-20100181533-A1 | Liquid-crystal compounds and LC media | VCL, LCT, NEFM | AKR1C3 3749/4885AKR1C2 4054/4885APP 1778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.