Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2741545 | 0.95 | TSHR (0.34) | ARCA1CA2CA5ACA9 | |
| SCHEMBL18735552 | 0.92 | CYP11B1 (0.32) | PTPN5CYP11B1CYP11B2NPBWR1PPARD | |
| SCHEMBL20380670 | 0.91 | PTGS2 (0.34) | CYP11B1CYP11B2NPBWR1PTGS2PDK2 | |
| SCHEMBL17548018 | 0.90 | PTPN5 (0.34) | PTPN5CYP1A2MAPTCYP2C19AR | |
| SCHEMBL16866174 | 0.90 | AKR1C3 (0.37) | PTPN5MAPTCYP2C19PTGS2PDK2 | |
| SCHEMBL20003578 | 0.90 | PTPN5 (0.31) | PTPN5CYP1A2MAPTCYP2C19AR | |
| SCHEMBL17548015 | 0.88 | PPARD (0.34) | PTPN5CYP1A2MAPTCYP2C19AR | |
| SCHEMBL2741564 | 0.87 | AKR1C3 (0.39) | CYP2C19 | |
| SCHEMBL20380602 | 0.86 | AKR1C3 (0.32) | HTR2ASLC6A4KCNH2PTGS2PTGS1 | |
| SCHEMBL4431222 | 0.86 | NFE2L2 (0.38) | PTPN5CYP1A2MAPTCYP2C19AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043782-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-11788009-B2 | Liquid-crystalline medium for use in a switching element | MERCK PATENT GMBH (DE) | 2023-10-17 | — | — | US | disclosed |
| US-11760931-B2 | Liquid-crystalline medium for use in a switching element | MERCK PATENT GMBH (DE) | 2023-09-19 | — | — | US | disclosed |
| US-11702597-B2 | Azo dye | MERCK PATENT GMBH (DE) | 2023-07-18 | — | — | US | disclosed |
| US-11667845-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2023-06-06 | — | — | US | disclosed |
| US-20230068853-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2023-03-02 | — | — | US | disclosed |
| US-20230029961-A1 | LIQUID CRYSTAL MEDIA COMPRISING POLYMERISABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-02-02 | — | — | US | disclosed |
| US-20220220383-A1 | METHOD FOR PREPARING A LIQUID CRYSTAL-BASED SWITCHING ELEMENT | MERCK PATENT GMBH (DE) | 2022-07-14 | — | — | US | disclosed |
| US-11359141-B2 | Additives for liquid crystal mixtures | MERCK PATENT GMBH (DE) | 2022-06-14 | — | — | US | disclosed |
| US-11353751-B2 | Double layer liquid crystal device and process of manufacture | MERCK PATENT GMBH (DE) | 2022-06-07 | — | — | US | disclosed |
| US-20150048276-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-02-19 | — | — | US | disclosed |
| US-20150048276-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-02-19 | — | — | US | disclosed |
| EP-2806011-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | DIC Corporation (JP) | 2014-11-26 | — | — | EP | disclosed |
| US-20140061534-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-03-06 | — | — | US | disclosed |
| US-20140061534-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-03-06 | — | — | US | disclosed |
| WO-2012052104-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |
| US-7972664-B2 | Liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-07-05 | — | — | US | disclosed |
| US-20100219375-A1 | LIQUID-CRYSTALLINE MEDIUM | WITTEK MICHAEL | 2010-09-02 | — | — | US | disclosed |
| US-7678431-B2 | Photostable liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2010-03-16 | — | — | US | disclosed |
| US-20070237907-A1 | PHOTOSTABLE LIQUID-CRYSTALLINE MEDIUM | MANABE ATSUTAKA | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667845-B2 | Liquid crystalline medium | NEFM, CCNI, MYT1 | PTPN5 3166/4885CYP1A2 295/4885MAPT 214/4885 |
| US-20230068853-A1 | LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY | CXCR1, PYM1, F11 | PTPN5 461/4885CYP1A2 541/4885MAPT 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.