Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29656856 | 0.83 | HTR3E (0.73) | MAPTRAB9AKMT2ANPC1LMNA | |
| SCHEMBL28599511 | 0.83 | HTR3E (0.73) | MAPTRAB9AKMT2ANPC1LMNA | |
| SCHEMBL22495384 | 0.82 | RAB9A (0.72) | MAPTRAB9AKMT2ANPC1LMNA | |
| SCHEMBL8931652 | 0.82 | MAPT (0.69) | MAPTRAB9AKMT2ANPC1ALDH1A1 | |
| SCHEMBL11066512 | 0.82 | MAPT (0.69) | MAPTRAB9AKMT2ANPC1LMNA | |
| SCHEMBL8890453 | 0.80 | GAA (0.69) | MAPTRAB9AKMT2ANPC1LMNA | |
| SCHEMBL12082184 | 0.80 | MAPT (0.69) | MAPTRAB9AKMT2ANPC1LMNA | |
| SCHEMBL6153220 | 0.80 | ALDH1A1 (0.66) | MAPTRAB9AKMT2ANPC1LMNA | |
| SCHEMBL11396473 | 0.79 | MAPT (0.65) | MAPTRAB9AKMT2ANPC1ALDH1A1 | |
| SCHEMBL8555604 | 0.79 | MAPT (0.65) | MAPTRAB9AKMT2ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1118138-A | Substituted azolone derivatives for treating diseases caused by helicobacter | JANSSEN PHARMACEUTICA NV (BE) | 1996-03-06 | — | — | CN | disclosed |