Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555924 | 0.80 | MAPT (0.53) | MAPTRAB9AKMT2ANPC1ALDH1A1 | |
| SCHEMBL8558558 | 0.78 | MAPT (0.61) | MAPTRAB9AKMT2ANPC1ALDH1A1 | |
| SCHEMBL8931652 | 0.75 | MAPT (0.69) | MAPTRAB9AKMT2ANPC1ALDH1A1 | |
| SCHEMBL23657747 | 0.74 | MAPT (0.72) | MAPTRAB9AKMT2ANPC1ALDH1A1 | |
| SCHEMBL6740893 | 0.73 | MAPT (0.86) | MAPTRAB9AKMT2AALDH1A1GAA | |
| SCHEMBL8890453 | 0.73 | GAA (0.69) | MAPTRAB9AKMT2ANPC1ALDH1A1 | |
| SCHEMBL14362730 | 0.72 | HTR3E (0.63) | MAPTRAB9AKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL424503 | 0.72 | DRD2 (0.66) | MAPTRAB9AKMT2ANPC1ALDH1A1 | |
| SCHEMBL8555321 | 0.72 | HRH4 (0.42) | MAPTALDH1A1HTR3ATDP1HSD17B10 | |
| SCHEMBL6153220 | 0.72 | ALDH1A1 (0.66) | MAPTRAB9AKMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| EP-0883606-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |
| WO-1997031893-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |