Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | KDM5C | P41229 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31222568 | 0.98 | LMNA (0.54) | LMNAALDH1A1SIGMAR1KDM5CKDM4C | |
| Hydrochloric Acid SCHEMBL6141847 | 0.98 | LMNA (0.58) | LMNAALDH1A1SIGMAR1KDM5CKDM4C | |
| SCHEMBL898696 | 0.92 | ALDH1A1 (0.54) | LMNAALDH1A1SIGMAR1KDM5CKDM4C | |
| SCHEMBL21044029 | 0.92 | ALDH1A1 (0.48) | LMNAALDH1A1SIGMAR1KDM5CKDM4C | |
| SCHEMBL6842740 | 0.86 | LMNA (0.54) | LMNAALDH1A1SIGMAR1BRD4HTR6 | |
| SCHEMBL7433040 | 0.85 | ALDH1A1 (0.67) | LMNAALDH1A1BRD4FOLH1HRH1 | |
| SCHEMBL11361974 | 0.83 | ALDH1A1 (0.65) | LMNAALDH1A1BRD4FOLH1KDM4E | |
| SCHEMBL7484815 | 0.82 | SIGMAR1 (0.60) | LMNAALDH1A1SIGMAR1KCNH2KDM4E | |
| SCHEMBL17911194 | 0.82 | ALDH1A1 (0.56) | LMNAALDH1A1BRD4FOLH1HRH1 | |
| SCHEMBL25145993 | 0.82 | LMNA (0.54) | LMNAALDH1A1SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1086698-C | Oxadiazoles, processes for their preparation and their use as medicaments | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-06-26 | — | — | CN | disclosed |
| CN-1233245-A | Oxadiazoles, processes for their preparation and their use as medicaments | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-10-27 | — | — | CN | disclosed |