Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27416833 | 0.86 | LMNA (0.55) | LMNASIGMAR1KDM4EALDH1A1HTT | |
| SCHEMBL2774515 | 0.85 | NPC1 (0.51) | LMNAKDM4EALDH1A1HTTMPO | |
| SCHEMBL16829428 | 0.85 | SIGMAR1 (0.45) | LMNASIGMAR1KDM4ERXFP1PARP1 | |
| SCHEMBL31222568 | 0.84 | LMNA (0.54) | LMNASIGMAR1KDM4EALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL6141847 | 0.84 | LMNA (0.58) | LMNASIGMAR1KDM4EALDH1A1HTT | |
| SCHEMBL2912053 | 0.84 | NPC1 (0.54) | KDM4EALDH1A1PARP1PARP2 | |
| SCHEMBL4878350 | 0.81 | HDAC3 (0.55) | LMNAKDM4EALDH1A1HTTHTR6 | |
| SCHEMBL2228234 | 0.81 | KDM4E (0.58) | LMNAKDM4EALDH1A1PARP1PARP2 | |
| SCHEMBL885730 | 0.81 | CYP2A13 (0.55) | LMNAKDM4EALDH1A1HTTMPO | |
| SCHEMBL25145993 | 0.81 | LMNA (0.54) | LMNASIGMAR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013082756-A1 | PHOSPHATE TRANSPORT INHIBITORS II | LEO PHARMA A/S (DK) | 2013-06-13 | — | — | WO | claimed |
| WO-2013082751-A1 | PHOSPHATE TRANSPORT INHIBITORS I | LEO PHARMA A/S (DK) | 2013-06-13 | — | — | WO | claimed |
| CN-107982266-A | Carbamate compounds and its preparation and application | 阿比德治疗公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-104159581-B | Carbamate compounds and methods of making and using the same | 阿比德治疗公司 | 2017-09-01 | — | — | CN | disclosed |
| US-6680318-B2 | FOR THERAPY OF PAIN, GASTROINTESTINAL DISORDERS, SPINAL INJURIES | ASTRAZENECA AB (SE) | 2004-01-20 | — | — | US | disclosed |