SCHEMBL27417243

SCHEMBL27417243

C=C(C)c1cc(F)c(C)c(F)c1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.48
HDAC6 Q9UBN7 2/20 0.48
CES2 O00748 2/20 0.32
CES1 P23141 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24931097 0.82 CES2 (0.50) HDAC1HDAC6CES2CES1
SCHEMBL7910357 0.80 VRK1 (0.34) HDAC1HDAC6CES2CES1
SCHEMBL12801786 0.79 CES2 (0.38) HDAC1HDAC6CES2CES1
SCHEMBL25064044 0.78 CES2 (0.31) CES2CES1
SCHEMBL18025416 0.76 HDAC1 (0.31) HDAC1HDAC6
SCHEMBL20076683 0.76 CYP3A4 (0.37) HDAC1HDAC6
SCHEMBL13125486 0.75 HDAC1 (0.59) HDAC1HDAC6CES2CES1
SCHEMBL13293496 0.75 TUBB1 (0.42)
SCHEMBL8282786 0.75 HDAC1 (0.53) HDAC1HDAC6CES2CES1
SCHEMBL28704685 0.75 KLKB1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024128040-A1 ACTIVE-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMATION METHOD, AND ELECTRONIC DEVICE PRODUCTION METHOD 富士フイルム株式会社 2024-06-20 WO disclosed