Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VRK1 | Q99986 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | SELL | P14151 | 1/20 | 0.31 |
| ▸ | SELP | P16109 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24931097 | 0.82 | CES2 (0.50) | CES2CES1HDAC1HDAC6 | |
| SCHEMBL27417243 | 0.80 | HDAC1 (0.48) | CES2CES1HDAC1HDAC6 | |
| SCHEMBL9742693 | 0.79 | KDM4E (0.46) | ESR1SELLSELPSELEHDAC1 | |
| SCHEMBL25064044 | 0.78 | CES2 (0.31) | CES2CES1 | |
| SCHEMBL3698143 | 0.77 | CES2 (0.33) | VRK1ESR1ESR2CES2CES1 | |
| SCHEMBL1373573 | 0.75 | CA5A (0.54) | CES2CES1ERN1SELLSELP | |
| SCHEMBL7882279 | 0.75 | SNCA (0.44) | ESR1ESR2 | |
| SCHEMBL12801786 | 0.75 | CES2 (0.38) | CES2CES1HDAC1HDAC6 | |
| SCHEMBL28704685 | 0.75 | KLKB1 (0.33) | — | |
| SCHEMBL16775694 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211328-B1 | IN PRESENCE OF AN ACID | GUN EI CHEMICAL INDUSTRY CO., LTD (JP) | 2001-04-03 | — | — | US | disclosed |