SCHEMBL20076683

SCHEMBL20076683

C=C(C)c1cc(C)c(Cl)c(F)c1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.37
CHRM1 P11229 1/20 0.37
ALOX15 P16050 1/20 0.37
MAOA P21397 1/20 0.37
TBXA2R P21731 1/20 0.37
ADRA1A P35348 1/20 0.37
HTR2B P41595 1/20 0.37
POLB P06746 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25064044 0.87 CES2 (0.31)
SCHEMBL19231915 0.79 CYP3A4 (0.39) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL12801786 0.79 CES2 (0.38) HDAC1HDAC6
SCHEMBL27417243 0.76 HDAC1 (0.48) HDAC1HDAC6
SCHEMBL18025416 0.76 HDAC1 (0.31) HDAC1HDAC6
SCHEMBL24931097 0.73 CES2 (0.50) HDAC1HDAC6
SCHEMBL26456874 0.73 KLKB1 (0.30)
SCHEMBL7910357 0.72 VRK1 (0.34) HDAC1HDAC6
SCHEMBL8282786 0.71 HDAC1 (0.53) HDAC1HDAC6
SCHEMBL19697623 0.71 MAOA (0.42) MAOAHTR2BPOLBHDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018071327-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-04-19 WO disclosed