Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24931097 | 0.86 | CES2 (0.50) | CES2CES1HDAC1HDAC6RAPGEF4 | |
| SCHEMBL27417243 | 0.79 | HDAC1 (0.48) | CES2CES1HDAC1HDAC6 | |
| SCHEMBL18025416 | 0.79 | HDAC1 (0.31) | HDAC1HDAC6 | |
| SCHEMBL20076683 | 0.79 | CYP3A4 (0.37) | HDAC1HDAC6 | |
| SCHEMBL13293382 | 0.78 | CES2 (0.48) | CES2CES1HDAC1HDAC6 | |
| SCHEMBL26456874 | 0.76 | KLKB1 (0.30) | — | |
| SCHEMBL17262495 | 0.75 | SORT1 (0.41) | — | |
| SCHEMBL7910357 | 0.75 | VRK1 (0.34) | CES2CES1HDAC1HDAC6 | |
| SCHEMBL8282786 | 0.74 | HDAC1 (0.53) | CES2CES1HDAC1HDAC6 | |
| SCHEMBL19697623 | 0.74 | MAOA (0.42) | CES2CES1HDAC1HDAC6ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011040510-A1 | INDAZOLE ANALOGUE | 旭化成ファーマ株式会社 (JP) | 2011-04-07 | — | — | WO | disclosed |