Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DBH | P09172 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30530049 | 0.85 | NAPRT (0.62) | NAPRTKCNQ3KCNQ2POLBPKM | |
| SCHEMBL14519853 | 0.85 | NAPRT (0.62) | NAPRTKCNQ3KCNQ2POLBPKM | |
| SCHEMBL1742846 | 0.82 | NAPRT (0.53) | NAPRTKCNQ3KCNQ2PIK3CDCYP2A6 | |
| SCHEMBL12418688 | 0.81 | KDM4E (0.56) | POLBSMN1; SMN2LMNAPDPK1KDM4E | |
| SCHEMBL1109095 | 0.80 | NAPRT (0.71) | NAPRTKCNQ3KCNQ2PIK3CDCYP2A6 | |
| SCHEMBL11307780 | 0.80 | CES2 (0.48) | SMN1; SMN2LMNAPDPK1KDM4EDBH | |
| SCHEMBL12582087 | 0.79 | MKNK1 (0.68) | CYP2A6MKNK1MKNK2 | |
| SCHEMBL5075261 | 0.79 | MKNK1 (0.66) | NAPRTKCNQ3KCNQ2PIK3CDMKNK1 | |
| SCHEMBL24198706 | 0.78 | NAPRT (0.49) | NAPRTKCNQ3KCNQ2PIK3CDPOLB | |
| SCHEMBL2952147 | 0.78 | KDM4E (0.50) | NAPRTKCNQ3KCNQ2SMN1; SMN2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356387-B1 | ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS | UNIV MONASH (AU) | 2024-06-26 | — | — | EP | disclosed |