Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515212 | 0.94 | CA2 (0.53) | CA2POLBIDO1MMP1MMP7 | |
| SCHEMBL11580921 | 0.82 | CA2 (0.50) | CA2CA1LMNACA9ALDH1A1 | |
| SCHEMBL11690780 | 0.82 | PTGS2 (0.55) | CA2POLBMMP8MMP12MMP13 | |
| SCHEMBL12821019 | 0.81 | POLB (0.58) | CA2POLBALDH1A1MEN1KMT2A | |
| SCHEMBL25702215 | 0.80 | ALDH1A1 (0.44) | CA2POLBIDO1ALDH1A1MAOA | |
| SCHEMBL66698 | 0.80 | CA2 (0.53) | CA2IDO1MMP1MMP7MMP8 | |
| SCHEMBL27568568 | 0.79 | CA2 (0.63) | CA2IDO1CA1CA12CA7 | |
| SCHEMBL5609865 | 0.79 | POLB (0.56) | CA2POLBMEN1KMT2AMAOA | |
| SCHEMBL28195609 | 0.78 | CA2 (0.52) | CA2POLBMMP1MMP8MMP13 | |
| SCHEMBL2342977 | 0.78 | CA2 (0.50) | CA2POLBCA1LMNACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100356979-C | Integrin expression inhibitors | EISAI CO LTD (JP) | 2007-12-26 | — | — | CN | disclosed |
| CN-1221533-C | Heterobicyclic sulfonamide derivative and sulfonic ester derivative | EISAI CO LTD (JP) | 2005-10-05 | — | — | CN | disclosed |
| CN-1217936-C | Heterocyclic compounds having sulfonic acid | EISAI CO LTD (JP) | 2005-09-07 | — | — | CN | disclosed |
| CN-1491941-A | Heterobicyclic sulfonamide derivative and sulfonic ester derivative | ������������ʽ���� | 2004-04-28 | — | — | CN | disclosed |
| CN-1414952-A | Heterocyclic compounds having sulfonic acid | EISAI CO LTD (JP) | 2003-04-30 | — | — | CN | disclosed |
| CN-1396833-A | Integrin expression inhibitors | EISAI CO LTD (JP) | 2003-02-12 | — | — | CN | disclosed |
| CN-1079097-C | Heterobicyclic sulfonamide derivatives and sulfonate derivatives | EISAI CO LTD (JP) | 2002-02-13 | — | — | CN | disclosed |
| CN-1114506-A | Heterobicyclic sulfonamide derivatives and sulfonate derivatives | EISAI CO LTD (JP) | 1996-01-03 | — | — | CN | disclosed |