SCHEMBL66698

SCHEMBL66698

O=S(=O)(Cl)CCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.53
IDO1 P14902 1/20 0.50
CA1 P00915 2/20 0.46
LMNA P02545 2/20 0.46
CA12 O43570 1/20 0.46
CA7 P43166 1/20 0.46
CA13 Q8N1Q1 1/20 0.46
CA9 Q16790 1/20 0.45
MMP1 P03956 1/20 0.44
MMP7 P09237 1/20 0.44
MMP8 P22894 1/20 0.44
MMP12 P39900 1/20 0.44
MMP13 P45452 1/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CASP1 P29466 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7829131 0.87 MMP12 (0.59) CA2CA1LMNAMMP8MMP12
SCHEMBL2356080 0.86 CA2 (0.56) CA2ALDH1A1KDM4E
SCHEMBL7958389 0.85 CA2 (0.50) CA2MAPT
SCHEMBL7958344 0.83 CA2 (0.53) CA2MAPT
SCHEMBL14437178 0.83 CA2 (0.53) CA2MAPT
SCHEMBL13159229 0.82 MGLL (0.61) CA2CA1LMNACA12CA7
SCHEMBL11580921 0.82 CA2 (0.50) CA2CA1LMNACA9ALDH1A1
SCHEMBL27568568 0.80 CA2 (0.63) CA2IDO1CA1LMNACA12
SCHEMBL27423912 0.80 CA2 (0.48) CA2IDO1CA1LMNACA12
SCHEMBL18884831 0.80 ALDH1A1 (0.48) CA2IDO1ALDH1A1HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912663-A Epoxy resin curing agent for corrosion prevention of stripping tower and preparation method thereof 江苏三木化工股份有限公司 2025-05-02 CN claimed
CN-119912662-A Epoxy resin curing agent for insulating castable and preparation method thereof 江苏三木化工股份有限公司 2025-05-02 CN claimed
EP-4741018-A2 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2026-05-13 EP disclosed
US-12583836-B2 Sulphonamide compounds Anaxis Pharma Pty Ltd (AU) 2026-03-24 US disclosed
EP-3728210-B1 ISOXAZOLE N-LINKED CARBAMOYL CYCLOHEXYL ACIDS AS LPA ANTAGONISTS BRISTOL MYERS SQUIBB CO (US) 2026-02-11 EP disclosed
EP-4168401-B1 SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2026-01-07 EP disclosed
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS SERVIER LAB (FR) 2026-01-01 US disclosed
US-20250388592-A1 (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS REMYND N.V. (BE) 2025-12-25 US disclosed
EP-4568968-A1 (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS Remynd N.V. (BE) 2025-06-18 EP disclosed
WO-2025120168-A1 SULFONAMIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF CRYPTOSPORIDIUM INFECTIONS INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (INRAE) (FR) 2025-06-12 WO disclosed
EP-4377295-B1 HALOACETHYDRAZIDES USEFUL AS AEP INHIBITORS HOFFMANN LA ROCHE (CH) 2025-06-11 EP disclosed
EP-0197800-A2 5-Thiaprostaglandins E1 and process for producing same TEIJIN LIMITED (JP) 1986-10-15 EP disclosed
EP-0122553-B1 N-SULPHENYL-PHENETHYL SULFONAMIDE BAYER AG (DE) 1986-02-26 EP disclosed
EP-0122553-A1 N-sulphenyl-phenethyl sulfonamide BAYER AG (DE) 1984-10-24 EP disclosed
EP-0112633-A2 Novel 5-thiaprostaglandin, process for production thereof, and pharmaceutical use thereof TEIJIN LIMITED (JP) 1984-07-04 EP disclosed
US-4443477-A ANTICOAGULANTS, ANTILIPEMIC AGENTS BOEHRINGER MANNHEIM GMBH (DE) 1984-04-17 US disclosed
EP-0079733-A2 Process for prostaglandin E1, production and novel delta 7-prostaglandines E and 7-hydroxyprostaglandins E TEIJIN LIMITED (JP) 1983-05-25 EP disclosed
US-4287342-A 2,4,6-Trihalo-5-alkyl-and 5-alkenylsulphonylpyrimidines CIBA-GEIGY CORPORATION (US) 1981-09-01 US disclosed
US-4188483-A 5-Alkylsulphonyl- and 5-alkenylsulphonylbarbituric acids and derivatives thereof CIBA-GEIGY CORPORATION (US) 1980-02-12 US disclosed
US-4163013-A Diphenylamine-azo-hydrocarbylsulfonylphenyl dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1979-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS BCL2, BCL2A1, BAX CA2 1189/4885IDO1 4559/4885CA1 1416/4885
US-12583836-B2 Sulphonamide compounds MLKL, RIPK3, CASP1 CA2 1637/4885IDO1 687/4885CA1 1409/4885
US-20250388592-A1 (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS SNCA, CHRNA6, CHRNA5 CA2 1348/4885IDO1 1970/4885CA1 271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.