Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15982396 | 0.98 | TRPA1 (0.34) | SIMGAMGAAMGAM2TRPA1 | |
| SCHEMBL15982397 | 0.83 | — | — | |
| SCHEMBL15314428 | 0.83 | OGA (0.38) | SIMGAMGAAMGAM2 | |
| SCHEMBL19976403 | 0.83 | SI (0.48) | SIMGAMTRPA1TRPM8 | |
| SCHEMBL15982404 | 0.80 | — | — | |
| SCHEMBL20273777 | 0.80 | SI (0.45) | SIMGAMTRPA1TRPM8 | |
| SCHEMBL22179332 | 0.80 | SI (0.45) | SIMGAMTRPA1TRPM8 | |
| SCHEMBL22174658 | 0.80 | SI (0.45) | SIMGAMTRPA1TRPM8 | |
| SCHEMBL10093807 | 0.80 | SI (0.45) | SIMGAMTRPA1TRPM8 | |
| SCHEMBL12868812 | 0.80 | SI (0.45) | SIMGAMTRPA1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218011-A1 | GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF | FIREFLY BIO, INC. | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240218011-A1 | GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF | NR3C1, NR3C2, MC2R | SI 4488/4885MGAM 3591/4885GAA 2646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.