SCHEMBL2742440

SCHEMBL2742440

CON(C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HTT P42858 1/20 0.44
CA4 P22748 2/20 0.39
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
FAAH O00519 1/20 0.38
PHGDH O43175 1/20 0.38
MGLL Q99685 1/20 0.38
LMNA P02545 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CHKA P35790 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
MAPT P10636 1/20 0.35
CA7 P43166 1/20 0.35
CA14 Q9ULX7 1/20 0.35
ALDH1A1 P00352 3/20 0.35
TSHR P16473 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28782958 0.80 MEN1 (0.46) MEN1KMT2AHTTCA4CA12
SCHEMBL27710108 0.76 MEN1 (0.42) MEN1KMT2AHTTCA12CA1
Methoxymethane SCHEMBL28242093 0.74 ALDH1A1 (0.56) MEN1KMT2AHTTCA4LMNA
SCHEMBL3951063 0.74 CA4 (0.41) MEN1KMT2AHTTCA4CA12
SCHEMBL210129 0.74 CA4 (0.41) MEN1KMT2AHTTCA4CA12
SCHEMBL1029861 0.74
SCHEMBL11412262 0.74 TDP1 (0.56) MEN1KMT2AL3MBTL1TDP1MAPT
SCHEMBL7867520 0.74 CA4 (0.42) MEN1KMT2AHTTCA4CA12
SCHEMBL1583518 0.74 CHRM5 (0.56) MEN1KMT2ALMNACHKAMAPT
SCHEMBL22415256 0.74 ACHE (0.46) MEN1KMT2ALMNATDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110218206-B Bisindolylmaleimide derivative and preparation method and application thereof 中国海洋大学 2022-03-04 CN claimed
CN-122074072-A Novel and cost-effective polycondensation of 2-methoxymethyl-p-phenylenediamine 威娜德国有限责任公司 2026-05-22 CN disclosed
US-20250282792-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO NEUROCRINE BIOSCIENCES, INC. 2025-09-11 US disclosed
WO-2025099119-A1 A NOVEL AND HIGHLY COST-EFFICIENT TELESCOPING SYNTHESIS OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE WELLA GERMANY GMBH (DE) 2025-05-15 WO disclosed
US-11713324-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2023-08-01 US disclosed
US-11220486-B2 Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof LA JOLLA INSTITUTE OF ALLERGY & IMMUNOLOGY (US) 2022-01-11 US disclosed
US-20210284653-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO NEUROCRINE BIOSCIENCES, INC. 2021-09-16 US disclosed
US-10941159-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2021-03-09 US disclosed
US-20210023043-A1 Methods of Treating Hyperalgesia TREVENA, INC. 2021-01-28 US disclosed
US-20200338084-A1 INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute 2020-10-29 US disclosed
US-20020022604-A1 Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade PHAMACIA CORPORATION 2002-02-21 US disclosed
US-5977132-A GALACTORRHEA, HYPERPROLACTINEMIC OVULATION, PROLACTINOMA AND BRAIN TUMORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-11-02 US disclosed
EP-0350166-A2 Polymer compositions NIPPON OIL CO., LTD. (JP) 1990-01-10 EP disclosed
EP-0022521-B1 PREPARATION OF CATIONIC TRIARYL METHANE DYESTUFFS BAYER AG (DE) 1982-09-15 EP disclosed
EP-0022521-A1 Preparation of cationic triaryl methane dyestuffs BAYER AG (DE) 1981-01-21 EP disclosed
US-4082739-A FIBRE-REACTIVE DYESTUFF CONTAINING A BIS-TRIAZINYLAMINO CIBA-GEIGY AG (CH) 1978-04-04 US disclosed
US-4076849-A AROMATIC SECONDARY AMINES CANADA PACKERS LIMITED (CA) 1978-02-28 US disclosed
US-3965087-A Trisazo dye containing a diphenylenesulfone structure SAKAI CHEMICAL INDUSTRY COMPANY LTD. (JA) 1976-06-22 US disclosed
US-3951941-A POLYAZODYE SAKAI CHEMICAL INDUSTRY COMPANY, LIMITED (JA) 1976-04-20 US disclosed
US-3947407-A ANTHRAQUINONE DYE CIBA-GEIGY AG (CH) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11220486-B2 Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof ACP1, PTPRCAP, PTPA MEN1 4778/4885KMT2A 567/4885HTT 3583/4885
US-20250282792-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO GNRHR, GHRHR, LHCGR MEN1 566/4885KMT2A 1468/4885HTT 1759/4885
US-11713324-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto GNRHR, GHRHR, LHCGR MEN1 566/4885KMT2A 1468/4885HTT 1759/4885
US-20210284653-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO GNRHR, GHRHR, LHCGR MEN1 566/4885KMT2A 1468/4885HTT 1759/4885
US-10941159-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto GNRHR, GHRHR, LHCGR MEN1 566/4885KMT2A 1468/4885HTT 1759/4885
US-20210023043-A1 Methods of Treating Hyperalgesia OPRL1, OPRK1, CHAT MEN1 4659/4885KMT2A 2264/4885HTT 476/4885
US-20200338084-A1 INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) AND USES THEREOF ACP1, PTPRCAP, PTPRO MEN1 4691/4885KMT2A 1214/4885HTT 3208/4885
US-20020022604-A1 Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade TFPI, PLAT, F2 MEN1 2078/4885KMT2A 3655/4885HTT 1457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.