Nitrous Acid

Nitrous Acid

SCHEMBL27425985

O=C(O)c1ccc(Br)nc1.O=NO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HA1 P13674 3/20 0.53
P4HTM Q9NXG6 2/20 0.53
MIF P14174 1/20 0.52
GABRP O00591 1/20 0.50
GABRD O14764 1/20 0.50
GABRA1 P14867 1/20 0.50
GABRB1 P18505 1/20 0.50
GABRG2 P18507 1/20 0.50
GABRB3 P28472 1/20 0.50
GABRA5 P31644 1/20 0.50
GABRA3 P34903 1/20 0.50
GABRA2 P47869 1/20 0.50
GABRB2 P47870 1/20 0.50
GABRA4 P48169 1/20 0.50
GABRE P78334 1/20 0.50
GABRA6 Q16445 1/20 0.50
GABRG1 Q8N1C3 1/20 0.50
GABRG3 Q99928 1/20 0.50
GABRQ Q9UN88 1/20 0.50
NAPRT Q6XQN6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29751460 0.92 P4HA1 (0.61) P4HA1P4HTMMIFGABRPGABRD
SCHEMBL38414 0.92 P4HA1 (0.61) P4HA1P4HTMMIFGABRPGABRD
Hydrochloric Acid SCHEMBL1871783 0.90 P4HA1 (0.59) P4HA1P4HTMMIFGABRPGABRD
SCHEMBL9035328 0.85 ALDH1A1 (0.55) P4HA1P4HTMMIFGABRPGABRD
SCHEMBL5973043 0.77 RXFP1 (0.44) P4HA1P4HTMMIFGABRPGABRD
6-Chloronicotinic Acid SCHEMBL27649626 0.77 NAPRT (0.85) P4HA1P4HTMMIFGABRPGABRD
Nitrous Acid SCHEMBL22129259 0.77 GABRP (0.85) P4HA1P4HTMMIFGABRPGABRD
SCHEMBL3500140 0.76 HCAR3 (0.69) HCAR3
SCHEMBL31078250 0.76 CPT1B (0.45) P4HA1P4HTMMIFGABRPGABRD
SCHEMBL2655448 0.76 CPT1B (0.45) P4HA1P4HTMMIFGABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1087904-A Carboxylic acid derivative, the pharmaceutical composition that contains these compounds with and preparation method thereof KRAL THOMAE GMBH (DE) 1994-06-15 CN disclosed