Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.63 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27480455 | 0.84 | LOXL2 (0.59) | LOXL2CYP4A11SMN1; SMN2KDM4EF10 | |
| SCHEMBL8626440 | 0.78 | HDAC8 (0.50) | RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL307892 | 0.78 | LOXL2 (1.00) | LOXL2CYP4F2CYP4A11SLC7A5HTR2C | |
| SCHEMBL29451790 | 0.78 | LOXL2 (1.00) | LOXL2CYP4F2CYP4A11SLC7A5HTR2C | |
| SCHEMBL8630144 | 0.77 | ERCC5 (0.47) | RAB9ASMN1; SMN2NPC1ALDH1A1CYP1A2 | |
| SCHEMBL27926873 | 0.77 | LOXL2 (0.69) | LOXL2CYP4F2CYP4A11SLC7A5HTR2C | |
| SCHEMBL8628090 | 0.77 | CES2 (0.59) | RAB9ASMN1; SMN2KDM4ENPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL307062 | 0.76 | LOXL2 (0.97) | LOXL2CYP4F2CYP4A11SLC7A5HTR2C | |
| Hydrochloric Acid SCHEMBL307891 | 0.76 | LOXL2 (0.97) | LOXL2CYP4F2CYP4A11SLC7A5HTR2C | |
| SCHEMBL3198121 | 0.76 | TSHR (0.52) | RAB9ASMN1; SMN2KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1109685-A | Process for producing lignan compound | SHIONOGI & CO (JP) | 1995-10-04 | — | — | CN | disclosed |