SCHEMBL27427372

SCHEMBL27427372

CCCCC(=O)Nc1ncncn1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.50
ADORA1 P30542 1/20 0.50
RAB9A P51151 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
MAPK10 P53779 1/20 0.49
HTT P42858 2/20 0.47
NCOA1 Q15788 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
ALDH1A1 P00352 1/20 0.46
LMNA P02545 2/20 0.44
NPC1 O15118 1/20 0.44
GLA P06280 1/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
DEGS1 O15121 1/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28269863 0.89 ADORA1 (0.47) ADORA1HTTALDH1A1LMNAMAPK1
SCHEMBL29029294 0.82 EPHX2 (0.40) SMN1; SMN2ADORA1RAB9AMEN1KMT2A
SCHEMBL9948617 0.81 LMNA (0.46) SMN1; SMN2ADORA1RAB9AMEN1KMT2A
SCHEMBL5651536 0.79 SMN1; SMN2 (0.51) SMN1; SMN2ADORA1RAB9AMEN1KMT2A
SCHEMBL31241118 0.79 RAB9A (0.66) SMN1; SMN2ADORA1RAB9AMEN1KMT2A
SCHEMBL22610228 0.79 LMNA (0.58) SMN1; SMN2ADORA1RAB9AKMT2AHTT
SCHEMBL16596333 0.77 LMNA (0.57) SMN1; SMN2RAB9AKMT2AHTTLMNA
SCHEMBL1993637 0.76 DEGS1 (0.64) SMN1; SMN2ADORA1RAB9AMEN1KMT2A
SCHEMBL12411456 0.76 L3MBTL1 (0.52) SMN1; SMN2ADORA1RAB9AKMT2AMAPK10
SCHEMBL2489636 0.75 ALDH1A1 (0.42) SMN1; SMN2RAB9AMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1103641-A A process for the preparation of 1,3,5-triazine carbamates from amino-1,3,5-triazines and organic carbonates CYTEC TECH CORP (US) 1995-06-14 CN disclosed