Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM4B | O94953 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23337439 | 0.80 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL14365376 | 0.79 | MEN1 (0.44) | ALDH1A1KDM4ETYMSMASP2MEN1 | |
| SCHEMBL28167702 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL13058007 | 0.76 | TYMS (0.47) | ALDH1A1TYMSMASP2MEN1NUDT1 | |
| SCHEMBL1202057 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10MAPTRXFP1 | |
| SCHEMBL6694499 | 0.74 | MASP2 (0.46) | ALDH1A1TYMSMASP2MEN1NUDT1 | |
| SCHEMBL30488147 | 0.72 | HSD17B10 (0.43) | ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL25273864 | 0.72 | HSD17B10 (0.43) | ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL8524830 | 0.71 | ESR1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL12377717 | 0.71 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1110305-C | Naphthyl-substituted benzimidazole derivatives as anticoagulants | BERLEX LAB (US) | 2003-06-04 | — | — | CN | disclosed |
| CN-1209062-A | Naphthyl-substituted benzimidazole derivatives as anticoagulants | BERLEX LAB (US) | 1999-02-24 | — | — | CN | disclosed |