Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | PGK2 | P07205 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10849592 | 0.86 | CA2 (0.56) | L3MBTL1MAOBCA2CA4CA5A | |
| Phosphoric Acid SCHEMBL3360478 | 0.84 | GPR84 (0.55) | MEN1KMT2AL3MBTL1MAPTGPR84 | |
| SCHEMBL27418397 | 0.80 | HTT (0.50) | L3MBTL1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL27397070 | 0.80 | MEN1 (0.47) | MEN1KMT2AL3MBTL1MAPTLMNA | |
| Pyrophosphoric Acid SCHEMBL28538003 | 0.79 | GPR84 (0.50) | MEN1KMT2AL3MBTL1MAPTGPR84 | |
| SCHEMBL27395625 | 0.78 | ALDH1A1 (0.50) | MEN1KMT2AL3MBTL1MAPTLMNA | |
| SCHEMBL756459 | 0.78 | CA2 (0.52) | MEN1KMT2AL3MBTL1MAPTGPR84 | |
| SCHEMBL16890178 | 0.78 | CYP1A2 (0.56) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL8151733 | 0.77 | RAB9A (0.50) | MAPTNPC1RAB9ATDP1PTPN1 | |
| SCHEMBL22480904 | 0.77 | MRGPRX4 (0.60) | MEN1KMT2AMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1089614-A | Alpha-phosphonosulfonate squalene synthetase inhibitors and method | SQUIBB & SONS INC (US) | 1994-07-20 | — | — | CN | disclosed |