Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.55 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205017 | 0.84 | HDAC1 (0.75) | GAAALDH1A1HDAC1HDAC8HDAC4 | |
| SCHEMBL5329565 | 0.82 | PGR (0.80) | PGRGAAHDAC1HDAC8HDAC3 | |
| SCHEMBL5607232 | 0.81 | PGR (0.64) | PGRHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL27754835 | 0.81 | PGR (0.64) | PGRHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL3756876 | 0.81 | PGR (1.00) | PGRALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL7181313 | 0.80 | PGR (0.73) | PGRHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL27889027 | 0.78 | ALDH1A1 (0.67) | GAAALDH1A1HDAC1HDAC8HDAC4 | |
| SCHEMBL28400969 | 0.78 | PGR (0.76) | PGRLMNAMAPTTDP1PKM | |
| SCHEMBL4813023 | 0.77 | HDAC3 (0.70) | PGRGAAHDAC1HDAC8HDAC3 | |
| SCHEMBL17894395 | 0.77 | PGR (0.62) | PGRHDAC1HDAC8HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1111453-A | Aryl sulfonamide derivatives and pharmaceutical compositions containing the same | NIPPON KOKAN KK (JP) | 1995-11-08 | — | — | CN | disclosed |