Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | DRD1 | P21728 | 3/20 | 0.32 |
| ▸ | DRD4 | P21917 | 3/20 | 0.32 |
| ▸ | DRD5 | P21918 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 3/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418498 | 0.83 | PTGS2 (0.43) | CXCR2KDM4EELANECXCR1PTGDR | |
| SCHEMBL27437226 | 0.80 | ELANE (0.40) | CXCR2KDM4EELANECXCR1PTGDR | |
| SCHEMBL8969655 | 0.79 | PTGDR (0.38) | CXCR2KDM4EELANECXCR1PTGDR | |
| SCHEMBL8422012 | 0.77 | PTGDR (0.37) | CXCR2KDM4EELANECXCR1PTGDR | |
| SCHEMBL8420646 | 0.76 | ALOX5 (0.34) | ELANEDRD2DRD1DRD4DRD5 | |
| SCHEMBL8420019 | 0.74 | KDM4E (0.39) | KDM4EELANEDRD2DRD1DRD4 | |
| SCHEMBL12848922 | 0.73 | PTGDR (0.36) | KDM4EELANEDRD2DRD1DRD4 | |
| SCHEMBL8969225 | 0.73 | ALDH1A1 (0.36) | KDM4EELANEDRD2DRD1DRD4 | |
| SCHEMBL2333663 | 0.73 | CXCR2 (0.52) | CXCR2CXCR1DRD2DRD1DRD4 | |
| SCHEMBL8772712 | 0.72 | KMT2A (0.39) | PTGDRPTGDR2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |