Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853259 | 0.79 | CARM1 (0.55) | HTR1AADRA1BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL9739959 | 0.78 | CARM1 (0.54) | HTR1AADRA1BSIGMAR1 | |
| SCHEMBL8297825 | 0.77 | HTR1A (0.50) | HTR1AADRA1BKDM4ESLC6A2SLC6A4 | |
| SCHEMBL23064518 | 0.77 | ADRA2C (0.55) | HTR1AADRA1BKDM4EHPGDALDH1A1 | |
| SCHEMBL27597994 | 0.76 | DRD2 (0.48) | HTR1AKDM4ETDP1ALDH1A1PLA2G1B | |
| SCHEMBL27597996 | 0.76 | KDM4E (0.66) | KDM4ETDP1GAAALDH1A1DRD4 | |
| Hydrochloric Acid SCHEMBL9134644 | 0.76 | HTR1A (0.49) | HTR1AADRA1BKDM4ESLC6A2SLC6A4 | |
| SCHEMBL8828503 | 0.75 | CYP2D6 (0.56) | HTR1AADRA1BKDM4ESLC6A4LMNA | |
| SCHEMBL31198346 | 0.75 | KEAP1 (0.48) | HTR1AADRA1BKDM4EGAAALDH1A1 | |
| SCHEMBL23064483 | 0.75 | KEAP1 (0.48) | HTR1AADRA1BKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1104637-A | Derivative of 2-aminopyrazine-5-carboxamide, preparation and pharmaceutical use of same | SYNTHELABO (FR) | 1995-07-05 | — | — | CN | disclosed |