Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
| ▸ | FLT4 | P35916 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744207 | 0.88 | HSD11B1 (0.43) | GAACA2CA1CA12CA9 | |
| SCHEMBL8014575 | 0.87 | HSD11B1 (0.38) | GAACA2CA1CA12CA9 | |
| SCHEMBL8011292 | 0.86 | KMT2A (0.41) | GAASMN1; SMN2CA2CA1MMP2 | |
| SCHEMBL7998459 | 0.86 | CA1 (0.38) | CA2CA1CA12CA9KMT2A | |
| SCHEMBL8008055 | 0.86 | FLT1 (0.41) | FLT1FLT4KDRKMT2AMAPT | |
| SCHEMBL8007957 | 0.86 | ALDH1A1 (0.41) | CA2CA1CA12CA9KMT2A | |
| SCHEMBL8010715 | 0.84 | CA12 (0.40) | FLT1FLT4KDRCA2CA1 | |
| SCHEMBL7998786 | 0.84 | HSD11B1 (0.36) | CA2CA1CA12CA9KMT2A | |
| SCHEMBL8009035 | 0.84 | HSD11B1 (0.36) | GAACA2CA1CA12CA9 | |
| SCHEMBL8010691 | 0.83 | HSD11B1 (0.37) | GAASMN1; SMN2FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6165668-A | N-[2-(1,2-benzisothiazol-3(2H)-ylidene 1,1-dioxide)-2-cyanoacetyl]benzenesulfonamide charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2000-12-26 | — | — | US | disclosed |