Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | S100A4 | P26447 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL513873 | 0.82 | P2RX7 (0.33) | LMNAHTTKDM4EPKM | |
| SCHEMBL9523842 | 0.79 | NPC1 (0.42) | KMT2ALMNAKDM4EALDH1A1HPGD | |
| SCHEMBL7013482 | 0.69 | — | — | |
| SCHEMBL2491687 | 0.68 | LMNA (0.63) | L3MBTL1MEN1KMT2ALMNAHTT | |
| SCHEMBL11316710 | 0.67 | HSD17B10 (0.45) | L3MBTL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2469218 | 0.66 | HSD17B10 (0.39) | L3MBTL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13503081 | 0.64 | KMT2A (0.36) | L3MBTL1MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL10954053 | 0.64 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL3881120 | 0.63 | — | — | |
| SCHEMBL6566994 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138546-C | Certain 1, 4, 5 -tri- substituted imidazole compounds useful as cytokine | ʷ��˿�������ȳ�ķ����˾ | 2004-02-18 | — | — | CN | disclosed |
| CN-1192147-A | Imidazole compounds | SMITHKLINE BEECHAM CORP (US) | 1998-09-02 | — | — | CN | disclosed |
| CN-1177299-A | Certain 1, 4, 5 -tri- substituted imidazole compounds useful as cytokine | SMITHKLINE BEECHAM CORP (US) | 1998-03-25 | — | — | CN | disclosed |