Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27442437 | 0.82 | L3MBTL1 (0.39) | PKMKDM4ELMNAHTT | |
| SCHEMBL9523842 | 0.76 | NPC1 (0.42) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL7013482 | 0.69 | — | — | |
| SCHEMBL512501 | 0.69 | NR3C2 (0.38) | NR3C2 | |
| SCHEMBL1594378 | 0.68 | LMNA (0.52) | P2RX7NR3C2NPC1PKMRAB9A | |
| SCHEMBL10504892 | 0.67 | GAA (0.40) | NPC1RAB9AGAAMAPTGFER | |
| SCHEMBL10985906 | 0.67 | IDO1 (0.33) | — | |
| SCHEMBL8320889 | 0.66 | LMNA (0.50) | P2RX7NR3C2NPC1PKMRAB9A | |
| Hydrochloric Acid SCHEMBL29102678 | 0.66 | LMNA (0.50) | P2RX7NR3C2NPC1PKMRAB9A | |
| SCHEMBL2469218 | 0.66 | HSD17B10 (0.39) | NPC1RAB9AGAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120027698-A9 | COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS | L'OREAL S.A. | 2012-02-02 | — | — | US | claimed |
| US-20100278764-A1 | COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS | L'OREAL S.A. | 2010-11-04 | — | — | US | claimed |
| US-20070264208-A1 | Cosmetic and/or pharmaceutical composition comprising at least one copolymer comprising at least one ionizable group, and cosmetic treatment process | L'OREAL S.A. (FR) | 2007-11-15 | — | — | US | claimed |
| US-20070189991-A1 | Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment | L'OREAL S.A. (FR) | 2007-08-16 | — | — | US | claimed |
| EP-1797868-A1 | Cosmetic composition comprising a (thio)urethane/(thio)urea copolymer capable of forming at least 3 hydrogen bonds, and process for cosmetic treatment | L'Oréal (FR) | 2007-06-20 | — | — | EP | claimed |
| EP-1797867-A1 | Cosmetic or pharmaceutical composition comprising a copolymer containing at least one ionisable group, and cosmetic treatment | L'Oréal (FR) | 2007-06-20 | — | — | EP | claimed |
| EP-3548544-B1 | AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS | OREAL (FR) | 2021-07-21 | — | — | EP | disclosed |
| US-10973751-B2 | Hair dyeing process comprising a pigment and an aqueous dispersion of supramolecular polymer | L'OREAL (FR) | 2021-04-13 | — | — | US | disclosed |
| US-20200108007-A1 | HAIR DYEING PROCESS COMPRISING A PIGMENT AND AN AQUEOUS DISPERSION OF SUPRAMOLECULAR POLYMER | L'OREAL (FR) | 2020-04-09 | — | — | US | disclosed |
| EP-3606502-A1 | HAIR DYEING PROCESS COMPRISING A PIGMENT AND AN AQUEOUS DISPERSION OF SUPRAMOLECULAR POLYMER | L'Oreal (FR) | 2020-02-12 | — | — | EP | disclosed |
| EP-3548544-A1 | AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS | L'OREAL (FR) | 2019-10-09 | — | — | EP | disclosed |
| US-20190274946-A1 | AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS | L'OREAL (FR) | 2019-09-12 | — | — | US | disclosed |
| US-10335361-B2 | Cosmetic process for making-up and/or caring for the skin and/or the lips | L'OREAL (FR) | 2019-07-02 | — | — | US | disclosed |
| WO-2010057920-A2 | METHOD FOR MAKING UP OR CARING FOR EYELASHES OR EYEBROWS USING A POLYALKENE-BASED SUPRAMOLECULAR POLYMER | L'OREAL (FR) | 2010-05-27 | — | — | WO | disclosed |
| EP-2189151-A1 | Process for the makeup of skin and/or lips by applying a composition comprising a supramolecular polymer | L'OREAL (FR) | 2010-05-26 | — | — | EP | disclosed |
| EP-2189148-A2 | Dye composition for keratin fibres comprising a supramolecular polymer based on polyalcene, a pigment and a volatile solvent | L'OREAL (FR) | 2010-05-26 | — | — | EP | disclosed |
| US-20070264208-A1 | Cosmetic and/or pharmaceutical composition comprising at least one copolymer comprising at least one ionizable group, and cosmetic treatment process | L'OREAL S.A. (FR) | 2007-11-15 | — | — | US | disclosed |
| US-20070189991-A1 | Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment | L'OREAL S.A. (FR) | 2007-08-16 | — | — | US | disclosed |
| EP-1797868-A1 | Cosmetic composition comprising a (thio)urethane/(thio)urea copolymer capable of forming at least 3 hydrogen bonds, and process for cosmetic treatment | L'Oréal (FR) | 2007-06-20 | — | — | EP | disclosed |
| EP-1797867-A1 | Cosmetic or pharmaceutical composition comprising a copolymer containing at least one ionisable group, and cosmetic treatment | L'Oréal (FR) | 2007-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190274946-A1 | AQUEOUS DISPERSION OF POLYALKENE SUPRAMOLECULAR POLYMER AND ITS USE IN COSMETICS | KRT18, DSG1, CUTA | P2RX7 4589/4885NR3C2 4816/4885NPC1 2151/4885 |
| US-20070189991-A1 | Cosmetic compositon comprising a (Thio)urethane/ (thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment | KRT18, TST, CTH | P2RX7 3977/4885NR3C2 4817/4885NPC1 4772/4885 |
| US-10973751-B2 | Hair dyeing process comprising a pigment and an aqueous dispersion of supramolecular polymer | TYR, NACA, POLR1C | P2RX7 4779/4885NR3C2 2314/4885NPC1 3058/4885 |
| US-20070264208-A1 | Cosmetic and/or pharmaceutical composition comprising at least one copolymer comprising at least one ionizable group, and cosmetic treatment process | KRT18, DSG1, DSC1 | P2RX7 4722/4885NR3C2 4772/4885NPC1 3377/4885 |
| US-10335361-B2 | Cosmetic process for making-up and/or caring for the skin and/or the lips | CUTA, DSG1, LPO | P2RX7 4605/4885NR3C2 4876/4885NPC1 2660/4885 |
| US-20120027698-A9 | COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS | KRT18, DSG1, DSC1 | P2RX7 4686/4885NR3C2 4791/4885NPC1 3503/4885 |
| US-20200108007-A1 | HAIR DYEING PROCESS COMPRISING A PIGMENT AND AN AQUEOUS DISPERSION OF SUPRAMOLECULAR POLYMER | TYR, NACA, POLR1C | P2RX7 4779/4885NR3C2 2314/4885NPC1 3058/4885 |
| US-20100278764-A1 | COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE COPOLYMER COMPRISING AT LEAST ONE IONIZABLE GROUP, AND COSMETIC TREATMENT PROCESS | KRT18, DSG1, DSC1 | P2RX7 4686/4885NR3C2 4791/4885NPC1 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.