Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | LAP3 | P28838 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792877 | 0.85 | ALDH1A1 (0.58) | ALDH1A1LMNAL3MBTL1PGRADORA3 | |
| SCHEMBL6792870 | 0.85 | ALDH1A1 (0.58) | ALDH1A1LMNAL3MBTL1PGRADORA3 | |
| SCHEMBL4007604 | 0.82 | ALDH1A1 (0.58) | ALDH1A1LMNAL3MBTL1PGRADORA3 | |
| SCHEMBL9234482 | 0.81 | LMNA (0.56) | ALDH1A1LMNAL3MBTL1PGRADORA3 | |
| SCHEMBL5182481 | 0.81 | LMNA (0.56) | ALDH1A1LMNAL3MBTL1PGRADORA3 | |
| SCHEMBL20425306 | 0.81 | MAOB (0.70) | ALOX5MAOBALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7401422 | 0.81 | LMNA (0.71) | ALOX5MAOBALDH1A1ACACBLMNA | |
| SCHEMBL27616913 | 0.80 | MAOB (0.56) | ALOX5MAOBACACBLMNAL3MBTL1 | |
| SCHEMBL6266373 | 0.79 | LTA4H (0.59) | ALOX5MAOBACACBLMNAL3MBTL1 | |
| SCHEMBL28968069 | 0.79 | PSEN1 (0.52) | ALDH1A1L3MBTL1PGRADORA3PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030911-B2 | Synthesis and biological activity of phosphoramidimidate and phosphoramidate DNA | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2024-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030911-B2 | Synthesis and biological activity of phosphoramidimidate and phosphoramidate DNA | RNASEH1, RNASE1, DNASE1 | ALOX5 1258/4885MAOB 2570/4885ALDH1A1 3210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.