Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Sorbic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 6/20 | 0.32 |
| ▸ | CNR1 | P21554 | 4/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sorbic Acid SCHEMBL30195487 | 1.00 | CA4 (0.43) | CA4CA1CA9FAHD1BBOX1 | |
| Sorbic Acid SCHEMBL5328357 | 1.00 | CA4 (0.43) | CA4CA1CA9FAHD1BBOX1 | |
| Sorbic Acid SCHEMBL28265777 | 0.97 | CA4 (0.41) | CA4CA1CA9FAHD1BBOX1 | |
| Sorbic Acid SCHEMBL29963629 | 0.97 | CA4 (0.38) | CA4CA1CA9FAHD1BBOX1 | |
| Sorbic Acid SCHEMBL28680231 | 0.97 | CA4 (0.38) | CA4CA1CA9FAHD1BBOX1 | |
| Sorbic Acid SCHEMBL41693 | 0.97 | — | — | |
| Sorbic Acid SCHEMBL29573362 | 0.97 | CA4 (0.40) | CA4CA1CA9FAHD1BBOX1 | |
| Sorbic Acid SCHEMBL3640 | 0.97 | — | — | |
| Sorbic Acid SCHEMBL929156 | 0.97 | CA4 (0.40) | CA4CA1CA9FAHD1BBOX1 | |
| Sorbic Acid SCHEMBL2353831 | 0.97 | CA4 (0.38) | CA4CA1CA9FAHD1BBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110358172-A | A kind of high rebound, the compound rubber-plastics material of low-gravity butyl renewable rubber and preparation method thereof | 江苏南翔橡胶制品有限公司 | 2019-10-22 | — | — | CN | claimed |
| CN-108179658-A | A kind of anti-mildew fresh-keeping body paper of non-staple food | 常德金德新材料科技股份有限公司 | 2018-06-19 | — | — | CN | claimed |
| CN-106466481-A | Sartans and NEPi complex | 叶莉 | 2017-03-01 | — | — | CN | claimed |
| CN-106390126-A | Pharmaceutical composition containing sartans and NEPi | 叶莉 | 2017-02-15 | — | — | CN | claimed |
| CN-114401724-A | Hypoglycemic medicine composition | 深圳信立泰药业股份有限公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-111821352-A | Chinese patent medicine for treating dog eczema | 成都中医药大学 | 2020-10-27 | — | — | CN | disclosed |
| CN-110358172-A | A kind of high rebound, the compound rubber-plastics material of low-gravity butyl renewable rubber and preparation method thereof | 江苏南翔橡胶制品有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-109393265-A | A kind of preparation method of anti-corrosion selenium-enriched konjac solid beverage | 安康学院 | 2019-03-01 | — | — | CN | disclosed |
| CN-108179658-A | A kind of anti-mildew fresh-keeping body paper of non-staple food | 常德金德新材料科技股份有限公司 | 2018-06-19 | — | — | CN | disclosed |
| CN-106466481-A | Sartans and NEPi complex | 叶莉 | 2017-03-01 | — | — | CN | disclosed |
| CN-106390126-A | Pharmaceutical composition containing sartans and NEPi | 叶莉 | 2017-02-15 | — | — | CN | disclosed |
| CN-106176654-A | Solid composite medicament containing compound A and preparation method thereof | 凌莉 | 2016-12-07 | — | — | CN | disclosed |
| CN-106176723-A | A kind of solid composite medicament and preparation method thereof | 凌莉 | 2016-12-07 | — | — | CN | disclosed |
| CN-106176724-A | A kind of stable solid composite medicament and preparation method thereof | 凌莉 | 2016-12-07 | — | — | CN | disclosed |
| CN-103505461-A | Solid medicine composition of lercanidipine and benazepril | SHENZHEN SALUBRIS PHARM CO LTD | 2014-01-15 | — | — | CN | disclosed |
| CN-1098044-C | Gelled foods and process for producing the same | OTSUKA FOOD CO LTD (JP) | 2003-01-08 | — | — | CN | disclosed |
| CN-1284838-A | Gelled foods and process for producing the same | OTSUKA FOOD CO LTD (JP) | 2001-02-21 | — | — | CN | disclosed |