Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Sorbic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 6/20 | 0.32 |
| ▸ | CNR1 | P21554 | 4/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sorbic Acid SCHEMBL5328357 | 1.00 | CA4 (0.43) | CA4CA1CA9FAHD1BBOX1 | |
| Sorbic Acid SCHEMBL27445812 | 1.00 | CA4 (0.43) | CA4CA1CA9FAHD1BBOX1 | |
| Sorbic Acid SCHEMBL28265777 | 0.97 | CA4 (0.41) | CA4CA1CA9FAHD1BBOX1 | |
| Sorbic Acid SCHEMBL29963629 | 0.97 | CA4 (0.38) | CA4CA1CA9FAHD1BBOX1 | |
| Sorbic Acid SCHEMBL28680231 | 0.97 | CA4 (0.38) | CA4CA1CA9FAHD1BBOX1 | |
| Sorbic Acid SCHEMBL41693 | 0.97 | — | — | |
| Sorbic Acid SCHEMBL29573362 | 0.97 | CA4 (0.40) | CA4CA1CA9FAHD1BBOX1 | |
| Sorbic Acid SCHEMBL3640 | 0.97 | — | — | |
| Sorbic Acid SCHEMBL929156 | 0.97 | CA4 (0.40) | CA4CA1CA9FAHD1BBOX1 | |
| Sorbic Acid SCHEMBL2353831 | 0.97 | CA4 (0.38) | CA4CA1CA9FAHD1BBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240315940-A1 | Topical Nourishing/Antimicrobial Compositions | LABORATORY SKIN CARE, INC. | 2024-09-26 | — | — | US | disclosed |
| EP-4404909-A1 | TOPICAL NOURISHING/ANTIMICROBIAL COMPOSITIONS | Laboratory Skin Care, Inc. (US) | 2024-07-31 | — | — | EP | disclosed |
| US-20230414512-A1 | Dermal Delivery Compositions Comprising Active Agent-Calcium Phosphate Particle Complexes and Methods of Using the Same | LABORATORY SKIN CARE, INC. | 2023-12-28 | — | — | US | disclosed |
| EP-4218718-A2 | DERMAL DELIVERY COMPOSITIONS COMPRISING ACTIVE AGENT-CALCIUM PHOSPHATE PARTICLE COMPLEXES AND METHODS OF USING THE SAME | Laboratory Skin Care, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2023049119-A1 | TOPICAL NOURISHING/ANTIMICROBIAL COMPOSITIONS | LABORATORY SKIN CARE, INC. (US) | 2023-03-30 | — | — | WO | disclosed |
| EP-2427178-B1 | DERMAL DELIVERY COMPOSITIONS COMPRISING ACTIVE AGENT-CALCIUM PHOSPHATE PARTICLE COMPLEXES AND METHODS OF USING THE SAME | LABORATORY SKIN CARE INC (US) | 2023-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240315940-A1 | Topical Nourishing/Antimicrobial Compositions | CUTA, POLR1C, NOS1 | CA4 133/4885CA1 1643/4885CA9 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.